19 of the Russian's 21 championships have been won on hard surfaces
A comeback the Russian player claimed his first trophy for nearly 30 months with victory over Corentin Moutet in the competition championship match.
The Russian, a ex- number one, has endured a difficult season, winning just one win at the big events and suffering a difficult moment at the American major.
His inconsistency on the ATP Tour - and issues with his serving in specific - led to him dropping out of the elite rankings and ultimately separating with long-term coach Gilles Cervara.
Now collaborating with Thomas Johansson and his other coach, he has consistently improved in the recent weeks - peaking in a closely contested three-set win over challenger Moutet.
This marks the player's initial trophy since the Rome competition and first on a hard court since spring of that year.
Victory also signifies the Russian has secured 21 titles at 21 different tournaments.
"This marks the first occasion I have attended a competition with my both daughters together, so to secure a title is really nice," commented world number 14 Daniil Medvedev.
"This title is in dedication of my second daughter her name, because the initial championship I got when my older daughter my daughter was born was for her."
The athlete, the 2021 US Open champion, had lost his past six finals, including in Halle previously this season.
His defensive play style and frequent reactions on court had caused some to question if his skill to play at the highest level was over.
But the player has implemented adjustments in recent weeks, making an effort to advance forward and perform positively, supported by an improved serving game.
He fought back from a deficit in the initial set against the difficult Frenchman, securing four of the final five points to take the lead.
Both players exchanged breaks in the following set before the challenger, attempting for his maiden tour championship, took control to force a decider.
The opponent defended 4 initial opportunities in a competitive third set before the Russian secured a break to 15 to secure the win.
Suitably, he secured the title with a rally at the net area, with his opponent unable to handle a shot after two hours and 38 minutes.